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Capabilities Statement · US Letter
The Human Foundation of Next-Generation Medicine
Federal Capabilities Statement
SAM.gov Registration renewal in progress
SAM.gov Registration renewal in progress
Est. 2016 · Heath, Ohio · Three Focus Areas
Human neural organoids
and the data they
make possible.
Animal models do not predict human brain disease — and that gap has driven decades of failed CNS translation. NEURXSTEM replaces approximation with human biology: patented whole-brain organoids that generate reproducible, regulator-grade molecular data.
UEI
YL6SLG1JKB37
CAGE
7FF36
Primary NAICS
541714
Primary PSC
AN12
Cong. District
Ohio 12
98–99%
reproducibility across lines and replicates
U.S. patent
the only issued patent on functional genomic human brain models
500+
validated disease biomarkers
Since 2015
complete human brain model, years ahead of FDA human-evidence standards
01Focus Areas
- 01 · Neural Organoid Platform & Models — NAICS 541714 · PSC AN12The patented NEURXSTEM Neural Organoid Platform (NNOP™) — full human brain architecture from retina to spinal cord, with the blood–brain barrier and microglia — delivered as frozen plates, live culture, or dataset-only.
- 02 · Medical & Translational R&D — NAICS 541714 · PSC AN13Human-validated molecular evidence for Alzheimer's, Parkinson's, migraine, autism, and opioid and substance use disorder — target identification, mechanism-of-action validation, biomarkers, and IND-supportive datasets.
- 03 · Longevity & AI Health Data — NAICS 541714 · PSC AN12Patented progeria-based accelerated-aging models and matched transcriptomic, metabolomic, and phenotypic datasets — a precise human-data layer for aging research and predictive AI.
02Differentiators
Whole-brain model
Retina, cortex, midbrain, hindbrain, cerebellum, spinal cord, and blood–brain barrier — not a region-limited organoid
Human, not animal
Direct concordance with clinical tissue (p < 10⁻¹⁰⁰), aligned with FDA human-data expectations
Reproducible at scale
98–99% reproducibility across lines and replicates, with standardized batch QC
Patent-protected
The only issued U.S. patent covering functional genomic human brain models
03Pathways to Engagement
Registered in SAM.gov; Registration renewal in progress. No SBA certifications, set-aside status, or GSA schedule held. Engagement is pursued through the pathways below.
SBIR / STTR
NIH, DoD, and other agency small-business R&D solicitations.
BAAs & OTAs
Broad agency announcements and other transaction authorities.
Grants & cooperative agreements
NIH, DoD medical research programs, BARDA, VA ORD.
Open-market R&D contracts
Direct award for studies, datasets, and modeling services.
04Platform in Practice
Translational R&D
Bench to Biomarker
Target identification, mechanism-of-action validation, and IND-supportive datasets built on organoid-derived evidence.
AI & Longevity
Clinically Corroborated Data
Matched transcriptomic, metabolomic, and phenotypic datasets stratified by ancestry, sex, and molecular subtype for predictive AI.
Federal R&D record: NIH SBIR award R44-DA051281 (NIDA, HEAL initiative). Additional past performance available upon request.
Corporate Data
Legal Name
NEURXSTEM, Inc.
Physical
785 Irving Wick Dr W · Heath, Ohio 43056-9492
Mailing
Same as physical
UEI
YL6SLG1JKB37
CAGE / NCAGE
7FF36
SAM.gov
Registration renewal in progress
Registration
All Awards
Entity Structure
Corporate Entity (Not Tax Exempt) · For Profit
Incorporation
Ohio / United States · Jul 1, 2016
Cong. District
Ohio 12
Fiscal YE
Dec 31
NAICS & PSC
541714
Research and Development in Biotechnology (except Nanobiotechnology) ★
AN12
R&D — Medical: Biomedical (Applied Research / Exploratory Development)
AN13
R&D — Medical: Biomedical (Advanced Development)
AN21
R&D — Medical: Drug Dependency (Basic Research)
AN31
R&D — Medical: Alcohol Dependency (Basic Research)
★ Primary · full list on the federal line card
Registration & Compliance
SAM.gov Registration in ProgressAll AwardsNo Active ExclusionsNo SBA Certifications HeldNo GSA Schedule
Points of Contact
Government Business POC
Dr. Rene Anand
Chief Executive Officer & Founder
Electronic Business POC
Dr. Rene Anand
Chief Executive Officer & Founder
Chief Medical Officer
Dr. Peter Cruse
Chief Medical Officer