
Focus Area
UEI YL6SLG1JKB37 · CAGE 7FF36
Focus Area 03 · NAICS 541714
Human data,
built for predictive AI.
Patent
Progeria-based aging models
NEURXSTEM's patented progeria-based accelerated-aging models replicate the hallmarks of aging in human neural tissue, paired with the matched transcriptomic, metabolomic, and phenotypic datasets generated across the NNOP™ platform. The result is a precise, clinically corroborated human-data layer for longevity research and for training and validating predictive AI health models. Animal models do not predict human brain disease — and that gap has driven decades of failed CNS translation. NEURXSTEM replaces approximation with human biology: patented whole-brain organoids that generate reproducible, regulator-grade molecular data.
01Scope of Work
- ▸Patented progeria-based accelerated-aging organoid models
- ▸Hallmarks-of-aging replication in human neural tissue
- ▸Matched transcriptomic, metabolomic, and phenotypic dataset licensing
- ▸Dataset stratification by ancestry, sex, and molecular subtype
- ▸Clinically corroborated training data for predictive AI health models
- ▸Longevity biomarker panel access from the 500+ validated marker library
- ▸Dataset-only delivery for computational and machine-learning programs
- ▸Custom dataset curation scoped to a sponsor's model architecture
02Engagement Model
Dataset licensing
Matched multi-omic datasets licensed for use in aging and longevity research programs.
AI training data packages
Clinically corroborated, reproducible datasets structured for predictive model training and validation.
Accelerated-aging model access
Progeria-based organoid models supplied as frozen plate or live culture for aging studies.
Stratified cohorts
Datasets segmented by ancestry, sex, and molecular subtype for subgroup-specific analysis.
03Federal Relevance
This focus area aligns with NIH's National Institute on Aging, DoD medical research programs with aging and resilience mandates, and BARDA and FDA initiatives exploring AI-enabled health tools built on human-derived data. Pathways include SBIR/STTR, BAAs, OTAs, grants and cooperative agreements, and open-market R&D contracts.
04Applicable Codes
541714R&D in Biotechnology (except Nanobiotechnology)
AN12R&D — Medical: Biomedical (Applied Research)
AN13R&D — Medical: Biomedical (Advanced Development)